This is a recreational trail with natural hazards - wildlife, weather, and temporary trail conditions that should be approached with caution. It is important that you pay attention as you ride. The most effective way to prevent mishaps is to adequately prepare for the trip. Knowledge of the area, weather, terrain, limitations of your body, plus a little common sense can help to ensure a safe and enjoyable trip.
You should know how to fix a flat tire (or travel with someone who does) and recognize poison ivy. You shouldn't have to worry about automobile traffic except between the trail and your lodging. It is a good idea to ride with others. The last few blocks to Point State Park in Pittsburgh will require navigating with traffic. Click here for a detailed street map of the City of Pittsburgh to help you navigate your way to Point State Park.
This link to the USDA Forest Service provides good outdoor safety information.